2013年09月-2018年06月 中国科学院水生生物研究所 硕博连读/博士学位
2009年09月-2013年06月 中国海洋大学水产学院 本科/学士学位
2020年01月至今 中国科学院水生生物研究所 博士后
鱼类遗传学与免疫学,近期主要以暗纹东方鲀、银鲫为研究对象,开展抗病育种、杂交育种等工作,已参与培育水产新品种一项(异育银鲫“中科5号”)。
《发育生物学》、《细胞生物学实验》
科研项目:
国家自然科学基金青年项目(主持,2022.01-2024.12)
中央高校基本科研业务费(自由探索专项)(主持,2021.01-2022.12)
江苏省自然科学基金青年项目(主持,2020.07-2023.06)
中国博士后科学基金面上资助(主持,2020-2022)
淡水生态与生物技术国家重点实验室开放课题(主持,2019.01-2019.12)
中国科学院LMB-LMM-LAMB联合资助开放课题(主持,2019.01-2020.12)
中央高校基本科研业务费(主持,2018.07-2019.12)
国家重点研发计划“水产养殖生物性别和发育的分子基础与调控机制”(参与,2018.12-2022.12)
国家自然科学基金“银鲫不同雌核生殖克隆系对鲫疱疹病毒抗性差异的调控机制研究”(参与,2018.01-2021.12)
中科院战略性先导科技专项子课题“抗病鲫新品种分子设计与培育”(参与,2013.07-2018.08)
中科院战略性先导科技专项子课题“高产鲫新品种设计与培育”(参与,2013.07-2018.08)
论文论著:
1. Fan-Xiang Gao, Wei-Jia Lu, Yan Shi, Hao-Yong Zhu, Yao-Hui Wang, Han-Qing Tu, Yang Gao, Li Zhou, Jian-Fang Gui, Zhe Zhao*. Transcriptome profiling revealed the growth superiority of hybrid pufferfish derived from Takifugu obscurus ♀ × Takifugu rubripes ♂. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 2021.
2. Fan-Xiang Gao, Wei-Jia Lu, Yan Shi, Li Zhou, Jian-Fang Gui, Zhe Zhao*. Identification and functional characterization of three irf7 transcript variants in obscure puffer (Takifugu obscurus). Developmental and comparative immunology 2021, 119, 104019.
3. Fan-Xiang Gao, Yan Shi, Wen Duan, Wei-Jia Lu, Wen Huang, Xiao-Juan Zhang, Zhe Zhao*, Li Zhou*, Jian-Fang Gui*. A rapid and reliable method for identifying genetic sex in obscure pufferfish (Takifugu obscurus). Aquaculture 2020, 519, 734749.
4. Fan-Xiang Gao, Wei-Jia Lu, Yang Wang, Qi-Ya Zhang, Yi-Bing Zhang, Chen-Yan Mou, Zhi Li, Xiao-Juan Zhang,Li Zhou*, Jian-Fang Gui*. Differential expression and functional diversification of diverse immunoglobulin domain-containing protein (DICP) family in three gynogenetic clones of gibel carp. Developmental and comparative immunology 2018, 84, 396-407.
5. Fan-Xiang Gao, Yang Wang, Qi-Ya Zhang, Cheng-Yan Mou, Zhi Li, Yuan-Sheng Deng, Li Zhou*, Jian-Fang Gui*. Distinct herpesvirus resistances and immune responses of three gynogenetic clones of gibel carp revealed by comprehensive transcriptomes. BMC Genomics 2017, 18, 561.
6. Wen Duan#, Fan-Xiang Gao#, Zi-Wei Chen, Yang Gao, Jian-Fang Gui, Zhe Zhao, Yan Shi*. A sex-linked SNP mutation in amhr2 is responsible for male differentiation in obscure puffer (Takifugu obscurus), Molecular Biology Reports 2021, 48, 6035–6046.
7. Wei-Jia Lu, Li Zhou, Fan-Xiang Gao, Yu-Lin Zhou, Zhi Li, Xiao-Juan Zhang, Yang Wang*, Jian-Fang Gui*. Dynamic and differential expression of duplicated Cxcr4/Cxcl12 genes facilitates antiviral response in hexaploid gibel carp. Frontiers in immunology 2020, 11, 2176.
8. Wei-Jia Lu,Fan-Xiang Gao,Yang Wang,Qi-Ya Zhang,Zhi Li,Xiao-Juan Zhang,Li Zhou*, Jian-Fang Gui*. Differential expression of innate and adaptive immune genes in the survivors of three gibel carp gynogenetic clones after herpesvirus challenge. BMC genomics 2019, 20.
9. Wei-Jia Lu, Li Zhou, Fan-Xiang Gao, Zhi-Hui Sun, Zhi Li, Xiao-Chun Liu, Shui-Sheng Li, Yang Wang*, Jian-Fang Gui*. Divergent expression patterns and function of two cxcr4 paralogs in hermaphroditic Epinephelus coioide. International Journal of Molecular Sciences2018, 19.
10. Cheng-Yan Mou, Yang Wang, Qi-Ya Zhang, Fan-Xiang Gao, Zhi Li, Jin-Feng Tong, Li Zhou*, Jian-Fang Gui. Differential interferon system gene expression profiles in susceptible and resistant gynogenetic clones of gibel carp challenged with herpesvirus CaHV. Developmental and Comparative Immunology 2018, 86, 52-64.
专利:
水产新品种 “异育银鲫中科5号”(GS-01-001-2017)
发明专利“一种快速鉴定暗纹东方鲀个体性别的SNP位点和引物及其方法”(CN201911078703.5)
表彰奖励:
2020年 河海大学疫情防控期间线上教学优秀教师
2018年 中国科学院大学“三好学生标兵”
2018年 中国科学院武汉教育基地“优秀毕业生”
2013年 中国海洋大学“优秀毕业生”