赵哲
发布时间:2017-03-03 浏览次数:
 

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赵哲,男,教授,研究生学历,博士学位

(Email:zhezhao@hhu.edu.cn;Tel:025-83787653)

 


 

简历

学习经历:

199909- 200307   安徽师范大学生命科学学院          本科/学士学位

200309- 200807   中国科学院水生生物研究所          研究生/博士学位

工作经历:

200807- 200810   南方医科大学生物技术学院             讲师

200810- 201007   中国科学院南海海洋研究所             博士后

201007- 201012   中国科学院南海海洋研究所             助理研究员

201012- 2016年08月   中国科学院南海海洋研究所             副研究员

201308- 201506   华盛顿州立大学Allen center           访问学者/博士后

201609- 至今               河海大学海洋学院                          教授

 


研究方向:

海洋生物技术,近期主要聚焦于海洋微生物致病机理及防控技术(快速检测技术和新型细菌素)、海洋微生物耐药性机理研究。

 


主讲课程:

 

 


主持的科研项目

1.  广东特支计划”科技创新青年拔尖人才项目,2016.06-2019.05

2.  国家自然科学基金面上项目,2013.01-2016.12

3.  广州市珠江科技新星专项项目,2013.07-2016.06

4.  中国科学院青年创新促进会会员专项,2012.01-2015.12

5.  国家自然科学基金青年项目,2010.01-2012.12

6.  广东省自然科学基金面上项目,2011.10-2013.09

7.  广东省科技计划项目(农业攻关), 2012.10-2014.09

8.  广东省中科院全面战略合作项目, 2011.07-2013.12

9.  广东省海洋渔业局鱼病专项项目,2013.01-2014.12

10. 中国博士后基金特别资助项目,2010.05-2012.04

11. 中国科学院院长优秀奖启动资金项目,2010.09-2011.08

12. 中国博士后基金一等资助项目,2010.05-2012.04

 


论文论著:

1.        Zhao Z, Orfe LH, Liu J, Lu SY, Besser TE, Call DR.2017.Microcin PDI regulation and proteolytic cleavage are unique among known microcins. Sci Rep.7:42529.

2.         Liu J, Lu SY, Orfe LH, Ren CH, Hu CQ, Call DR, Avillan JJ, Zhao Z*.2016. ExsE Is a Negative Regulator for T3SS Gene Expression in Vibrio alginolyticus.Front Cell Infect Microbiol.6:177.(*Corresponding author)

3.         Liu J, Zhao Z, Orfe L, Subbiah M, Call DR. 2016. Soil-borne reservoirs of antibiotic-resistant bacteria are established following therapeutic treatment of dairy calves. Environ Microbiol.18(2):557-64.

4.        Zhang H, Li L, Zhao Z, Peng D, Zhou X. 2016. Polar flagella rotation in Vibrio parahaemolyticus confers resistance to bacteriophage infection. Sci Rep. 6:26147.

5.        Zhao Z, Eberhart LJ, Orfe LH, Lu SY, Besser TE, Call DR. 2015. Genome-wide screening identifies six genes that are associated with susceptibility to Escherichia coli Microcin PDI. Appl Environ Microbiol. 81(20):6953-63. 

6.        Wang YH, Zhao Z, Zhang LP, Hu CQ, Ren CH, Yuan LH. 2014. Molecular characterization of metallothionein from white shrimp, Litopenaeus vannamei and its expression response to salinity stress. Marine Biology Research 10(7),731–737

7.        Shi Y, Zhao Z, Hong XY, Chen KC, Zhu XP. 2014. Characterization and Functional Analysis of Voltage-Dependent Anion Channel 1 (VDAC1) from Orange-Spotted Grouper (Epinephelus coioides). J Biochem Mol Toxicol, 28(7):292-301.

8.         Yu M, Ren CH, Qiu J, Luo P Zhu R, Zhao Z*. 2013. Draft Genome Sequence of the Opportunistic Marine Pathogen Vibrio harveyi Strain E385. Genome Announc.1 (6): e00677-13. (* corresponding author)

9.        Shi Y, Zhao Z, Zhu XP, Chen KC, Zhang QY. 2013. Expression and functional characterization of a gene associated with retinoid-interferon-induced mortality 19 (GRIM-19) from orange-spotted grouper (Epinephelus coioides). Fish Shellfish Immunol. 34(1):273-279.

10.    Zhao Z, Zhang LP, Ren CH, Zhao JJ, Chen C, Jiang X, Luo P, Hu CQ. 2011. Autophagy is induced by the type III secretion system of Vibrio alginolyticus in several mammalian cell lines. Archives of microbiology, 193: 53-61.

11.    Zhao Z, Chen C, Hu CQ, Ren CH, Zhao JJ, Zhang LP, Jiang X, Luo P, Wang Q. 2010. The type III secretion system of Vibrio alginolyticus induces rapid apoptosis, cell rounding, and osmotic lysis of fish cells. Microbiology-SGM, 156: 2864-2872.

12.    Zhao Z, Ke F, Shi Y, Zhou GZ, Gui JF, Zhang QY. 2009. Rana grylio virus thymidine kinase gene: an early gene of iridovirus encoding for a cytoplasmic protein. Virus genes, 38: 345-352.

13.    Zhao Z, Ke F, Huang YH, Zhao JG, Gui JF, Zhang QY. 2008. Identification and characterization of a novel envelope protein in Rana grylio virus. Journal of General Virology, 89:1866 -1872.

14.    Zhao Z, Shi Y, Ke F, Sun W, Gui JF, Zhang QY. 2008. Constitutive expression of thymidylate synthase from LCDV-C induces a transformed phenotype in fish cells. Virology, 372:118-126.

15.    Zhao Z, Ke F, Li ZQ, Gui JF, Zhang QY. 2008. Isolation, characterization and genome sequence of a birnavirus strain from flounder Paralichthys olivaceus in China. Archives of Virology, 153: 1143-1148.

16.    Zhao Z, Ke F, Gui JF, Zhang QY. 2007. Characterization of an early gene encoding for dUTPase in Rana grylio virus. Virus Research, 123: 128-137.

17.    Shi Y, Zhao Z, Yin JK, Zhu XP, Chen KC, Pan DB, Gui JF. 2010. Interferon regulatory factor-2 in orange-spotted grouper (Epinephelus coioides): gene, inductive expression pattern and subcellular localization. Comp Biochem Physiol., 155:110-117.

18.    Ke F, Zhao Z, Zhang QY. 2009. Cloning, expression and subcellular distribution of a Rana grylio virus late gene encoding ERV1 homologue. Molecular Biology Reports, 36: 1651-1659.

19.    Zhang QY, Zhao Z, Xiao F, Li ZQ, Gui JF. 2006. Molecular characterization of three Rana grylio virus (RGV) isolates and Paralichthys olivaceus lymphocystis disease virus in (LCDV-C) iridoviruses. Aquaculture, 251:1-10.

20.    Shi Y, Zhang YB, Zhao Z, Jiang J, Zhang QY, Gui JF. 2008. Molecular characterization and subcellular localization of Carassius auratus interferon regulatory factor-1. Dev Comp Immunol, 32: 134–146.

21.    Sun W, Huang YH, Zhao Z, Gui JF, Zhang QY. 2006. Characterization of the Rana grylio virus 3β-HSD and its novel role in suppressing virus-induced cytopathic effect. Biochemical & Biophysical Research Communications, 351: 44-50.

22.    Jiang X, Ren CH, Hu CQ, Zhao Z. 2014. Isolation and algicidal characterization of Bowmanella denitrificans S088 against Chlorella vulgaris. World J Microbiol Biotechnol. 30(2):621-629.

23.    Ren CH, Jiang X, Sun HY, Luo P, Zhao Z, Hu CQ. 2012. Detection and characterization of two insertion sequences in Vibrio alginolyticus. Annals of Microbiology. 2012, 62: 69-75.

24.    Zhao JJ, Chen C, Luo P, Ren CH, Jiang X, Zhao Z, Hu CQ. 2011. SYBR Green I-based real-time PCR targeting the rpoX gene for sensitive and rapid detection of Vibrio alginolyticus. Mol Cell Probes. 25(2-3):137-41.

25.    Wen J, Hu CQ, Zhang LP, Luo P, Zhao Z, Fan SG, Su T. 2010. The application of PCR–RFLP and FINS for species identification used in sea cucumbers (Aspidochirotida: Stichopodidae) products from the market. Food Control, 21: 403-407.

26.    Zhao JG. Zhou L, Jin JY, Zhao Z, Lan J, Zhang YB, Zhang QY, Gui JF. 2009. Antimicrobial activity-specific to Gram-negative bacteria and immune modulation -mediated NF-κB and Sp1 of a medaka β-defensin. Dev Comp Immunol, 33: 624-637.

27.    Wen J, Zeng L,SunYL, Chen DH, Xu YH, Luo P, Zhao Z, Yu ZH, Fang SG. 2015. Authentication and traceability of fish maw products from the market using DNA sequencing. Food Control, 55:185–189.

28.    Jiang HY, Hu CQ, Yang HP, Zhang LP, Peng PF, Luo P, Zhao Z, Xia JJ. 2015. Morphology and phylogeny of Halamphora yongxingensis sp. nov. (Bacillariophyta), a new marine benthic diatom isolated from Yongxing Island, South China Sea. Phytotaxa 195 (1): 053–064.

参编论著:

张奇亚, 赵哲. 2013. 第三节 鱼类病毒分子生物学. pp259-274.  In 鱼病学 (汪建国主编), 中国农业出版社, 北京.

授权专利:

1. 赵哲,任春华,胡超群,张吕平,罗鹏,江晓。一种用于检测对虾白斑综合症病毒的试剂盒及检测方法。 授权号:ZL200910042205.5

2. 赵哲,任春华,胡超群,江晓,张吕平,罗鹏。一种用于检测对虾桃拉病毒的LAMP试剂盒及其检测方法。授权号:ZL201010105752.6

3. 赵哲, 李红梅, 刘助红, 江晓, 任春华,胡超群。传染性皮下及造血组织坏死病毒的LAMP检测引物组、检测试剂盒及检测方法。授权号:ZL201310477057.6

4. 赵哲,胡超群, 任春华, 江晓, 邓益琴。一种受渗透压调控的启动子PmccPDI及其重组表达载体及应用。申请号:201510875053.2

 


获奖及个人荣誉:

1. 2016年 广东省培养高层次人才特殊支持计划(青年拔尖人才)

2. 2013年 广东省技术发明一等奖(排名第六)

3. 2012年 广州市珠江科技新星称号

4. 2011年 中国科学院青年创新促进会会员

5. 2010年 中国科学院王宽诚人才奖

6. 2009年 湖北省优秀博士学位论文奖

7. 2008年 中国科学院院长优秀奖

 


学术兼职: