（Email: 20210073@hhu.edu.cn，海洋科学实验中心209室 ）
学习经历：
2013.09-2016.07 中国科学院大学海洋研究所，海洋生物学专业，获理学博士学位
2010.09-2013.07 中国科学院大学海洋研究所，海洋生物学专业，获理学硕士学位
2004.09-2008.07 西南大学，生命科学学院，生物技术专业，获理学学士学位
工作经历：
2021.10-至今 河海大学，海洋学院，副教授
2019.12-2021.07 大连海洋大学，水产与生命学院，副研究员
2016.10-2019.11 大连海洋大学，水产与生命学院，助理研究员
研究方向：
1. 海洋生物活性肽的分离及功能鉴定；
2. 海洋动物的免疫系统和代谢的相互作用及调控机制研究
主讲课程：
研究生课程：《海洋生物学》；
本科生课程：《海洋动物生理学》、《发育生物学》、《细胞生物学实验》
科研项目：
1. 江苏省农业农村厅, 种业振兴“揭榜挂帅”项目，高品质高产河鲀新品种的创制及育繁推体系的构建，380万元，参与；
2. 江苏省农业科学院，大宗淡水鱼越冬综合征的发病机制及绿色防控关键技术研究，150万元，参与；
3. 企事业单位委托科技项目，废水资源化处理技术研发合同，40万元，主持
4. 企事业单位委托科技项目，免疫增强剂的研发及应用，20万元，主持
5. 江苏省自然资源厅，江苏沿海滩涂微生物资源调查与多样性研究，129万元，参与；
6. 国家自然科学基金（青年基金），中华绒螯蟹GATA转录因子及其磷酸化修饰对造血过程的调控作用，26万元，已结题，主持；
7. 国家重点研发计划，牡蛎扇贝抗病性状遗传与分子机制，55万元，已结题，主持；
8. 辽宁省自然科学基金计划重点项目，Toll样受体2对长牡蛎吞噬细胞的功能和分裂增殖的调控作用，5万 元，已结题，主持；
科研奖励：
2020年度高等学校科学研究优秀成果奖（自然科学奖），二等奖
论文论著：
Xiaorui Song, Yaxing Yang, Nan Cui, Tianying Lei, Xingkun Jin, Ying Huang, Yan Shi, Zhe Zhao*,Emerging role of lipid droplets in Obscure puffer immune response against Vibrio harveyi. Mar Life Sci Tech, 2024 Jan, https://doi.org/10.1007/s42995-025-00286-w;
Nan Cui, Tianying Lei, Lanyue Liang, Xingkun Jin, Yan Shi, Zhe Zhao, Xiaorui Song*, Type I Interferon (IFNd) enhanced the innate immune response and induced lipid droplets formation in obscure puffer Takifugu obscurus, Dev Comp Immunol. 163 (2025) 105321
Xiaorui Song†, Tianying Lei†, Nan Cui, Xingkun Jin, Ying Huang, Yan Shi, Zhe Zhao*, A preliminary investigation on the protective effects of β-glucan and mannan induced trained immunity in pufferfish Takifugu obscurus. Fish Shellfish Immunol. 156 (2025) 110035
Meng-Han Huang; Dao-Feng Zhang; Hong-Chuan Wang; Wei He; Xiao-Rui Song*. Description of Rhodobacter flavimaris sp. nov. and proposal of the genera Paenirhodobacter, Sedimentimonas, and Sinirhodobacter as synonyms of Rhodobacter. Int J Syst Evol Microbiol. 2024 Oct;74(10)
Yang Y, Song X, Cui N, Lei T, Huang Y, Shi Y, Hu Y, Zhou X, Zhao Z. Functional characterization of obscure puffer ToNK-lysin: A novel immunomodulator possessing anti-bacterial and anti-inflammatory properties. Fish Shellfish Immunol. 2023 Nov; 142:109080. doi: 10.1016/j.fsi.2023.109080.
Xiaorui Song, Ying Song, Miren Dong, Zhaoqun Liu, Weilin Wang, Lingling Wang, Linsheng Song*, A new member of the runt domain family from Pacific oyster Crassostrea gigas (CgRunx) potentially involved in immune response and larvae hematopoiesis. Fish Shellfish Immunol. 2019 Jun; 89:228-236.
Xiaorui Song#, Xiaoyu Xin#, Hao Wang, Hui Li, Huan Zhang, ZhihaoJia, Conghui Liu, Shuai Jiang, Lingling Wang, Linsheng Song*, A single-CRD C-type lectin (CgCLec-3) with novel DIN motif exhibits versatile immune functions in Crassostrea gigas. Fish Shellfish Immunol. 2019 Jul 3. 92:772-781. (co-first author)
Song Xiaorui, Liu Zhaoqun, Wang Lingling, Song Linsheng*, Recent Advances of Shell Matrix Proteins and Cellular Orchestration in Marine Molluscan Shell Biomineralization. Frontiers in Marine Science. 2019, 6:41.
Wang Lingling#, Song Xiaorui#, Song Linsheng. The oyster immunity [J]. Dev Comp Immunol. 2018 Mar; 80:99-118. (co-first author）
Song Xiaorui, Xin X, Dong M, Wang W, Wang L, Song L. The ancient role for GATA2/3 transcription factor homolog in the hemocyte production of oyster. Dev Comp Immunol. 2018 Jan 6; 82: 55-65.
Song Xiaorui, Wang Hao, Xin Lusheng, Xu Jiachao, Li hui, Zhang tao, Wang Lingling, Song Linsheng*. The immunological capacity in the Larvae of Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 2016 Feb;49: 461-469.
Song Xiaorui, Wang Weilin, Song Linsheng. (2019). Hematopoiesis and regulatory signaling in molluscs. Fish & Shellfish Immunology. 91. 462.
Song Xiaorui, Wang Hao, Chen Hao, Sun Mingzhe, Liang Zhongxiu, Wang Lingling, Song Linsheng*. Conserved hemopoietic transcription factor Cg-SCL delineate hematopoiesis of Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 2016; 51:180-188.
Xiaorui Song, Xiaotong Wang, Li Li, Guofan Zhang*. Identification two novel nacrein-like proteins involved in the shell formation of the Pacific oyster Crassostrea gigas [J]. Mol Biol Rep. 2014, 41(7): 4273-4278.
Xiaotong Wang#, Xiaorui Song#, Li Li, and Guofan Zhang*. An improved method of DNA extraction from the shell of the Pacific oyster, Crassostrea gigas. The Israeli Journal of Aquaculture-Bamidgeh, IJA. 2012; 64: 800 (co-first author）
Xiaotong Wang#, Xiaorui Song#, Tong Wang, Qihui Zhu, Guoying Miao, Yuanxin Chen, Xiaodong Fang, Huayong Que, Li Li*, Guofan Zhang, Evolution and functional analysis of the Pif97 gene of the Pacific oyster Crassostrea gigas. Curr Zool. 2013, 59 (1): 109-115 (co-first author）
